Selective Oestrogen Replacement Modulators (SERMs)

SERMs are medications that act similarly to oestrogen on certain parts of the body and block the effects of oestrogen on other parts of the body.

Ospemifene is a SERM that has its effect on the vagina and is taken orally rather than vaginally. It is a treatment for genitourinary syndrome of the menopause.

Duavive is a combination tablet consisting of conjugated oestrogen (oestrogen derived synthetically or from the urine of pregnant mares) and the SERM bazedoxifene which blocks the actions of oestrogen on the womb. It is licenced for menopausal symptoms for women who are intolerant to progesterone